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Top 10 life saving drugs

Discover the top 10 life-saving drugs every GPAT aspirant must know for 2025! This expert-curated list covers essential emergency medicines, their mec
Top 10 Life-Saving Drugs for Pharmacy & GPAT 2025 | ExPharma.in

💊 Top 10 Life-Saving Drugs Every Pharmacy Student Must Know in 2025

If you're a B.Pharm student or preparing for GPAT 2025, understanding emergency and life-saving drugs is essential. These drugs are frequently asked in GPAT, NIPER, and university exams – and they’re used in real-life emergencies too!

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1. Adrenaline (Epinephrine)

  • MOA: Alpha & Beta adrenergic receptor agonist
  • Uses: Anaphylaxis, cardiac arrest
  • Side Effects: Tachycardia, tremors

2. Aspirin

  • MOA: Irreversible COX inhibitor
  • Uses: MI prevention, antiplatelet
  • Side Effects: GI bleeding, Reye’s syndrome

3. Atropine

  • MOA: Muscarinic receptor blocker
  • Uses: Bradycardia, organophosphate poisoning
  • Side Effects: Dry mouth, blurred vision

4. Regular Insulin

  • MOA: Stimulates glucose uptake via insulin receptors
  • Uses: Diabetic ketoacidosis (DKA), hyperkalemia
  • Note: Only insulin given IV

5. Nitroglycerin

  • MOA: Releases NO → venodilation
  • Uses: Angina pectoris, acute coronary syndrome
  • Side Effects: Headache, hypotension

6. Activated Charcoal

  • MOA: Adsorbs toxins in GI tract
  • Uses: Acute poisoning
  • Note: Most effective within 1 hour of ingestion

7. Naloxone

  • MOA: Pure opioid antagonist (μ-receptor)
  • Uses: Opioid overdose (e.g., morphine, heroin)
  • Note: Shorter half-life than opioids

8. Salbutamol (Albuterol)

  • MOA: Beta-2 adrenergic agonist → bronchodilation
  • Uses: Asthma, bronchospasm
  • Side Effects: Tachycardia, hypokalemia

9. Ceftriaxone

  • MOA: Inhibits bacterial cell wall synthesis (3rd gen cephalosporin)
  • Uses: Meningitis, pneumonia, gonorrhea
  • Note: Long half-life, once daily dosing

10. Diazepam

  • MOA: Enhances GABA-A receptor activity
  • Uses: Status epilepticus, anxiety, alcohol withdrawal
  • Side Effects: Sedation, dependence

📌 Summary Table:

Drug Use MOA
AdrenalineAnaphylaxisAdrenergic Agonist
AspirinMI preventionCOX Inhibitor
AtropineOP PoisoningMuscarinic Blocker
InsulinDKAGlucose Uptake ↑
NitroglycerinAnginaNO Donor
CharcoalPoisoningToxin Adsorption
NaloxoneOpioid OverdoseOpioid Antagonist
SalbutamolAsthmaBeta-2 Agonist
CeftriaxoneBacterial InfectionsCell Wall Inhibition
DiazepamSeizuresGABA Enhancement

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Tags: GPAT 2025, Pharmacology, Life Saving Drugs, Pharmacy Notes, ExPharma.in, Pocket GPAT, B.Pharm, MCQs, Pharmacology Notes, Emergency Medicines

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